Diisopropylamine

Diisopropylamine
Skeletal formula of diisopropylamine
Identifiers
CAS number	108-18-9 7pxY
PubChem	7912
ChemSpider	7624 7pxY
UNII	BR9JLI40NO 7pxY
EC number	203-558-5
UN number	1158
RTECS number	IM4025000
Beilstein Reference	605284
Jmol-3D images	Image 1
SMILES CC(C)NC(C)C <p><p style="word-wrap: break-word;">
InChI InChI=1S/C6H15N/c1-5(2)7-6(3)4/h5-7H,1-4H3 7pxY Key: UAOMVDZJSHZZME-UHFFFAOYSA-N 7pxY
Thermochemistry
Std enthalpy of formation ΔfHo298	−173.6–−168.4 kJ mol−1
Std enthalpy of combustion ΔcHo298	−4.3363–−4.3313 MJ mol−1
Hazards
GHS pictograms	The flame pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) The corrosion pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) The exclamation-mark pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
GHS signal word	DANGER
GHS hazard statements	H225, H302, H314, H332
GHS precautionary statements	P210, P280, P305+351+338, P310
EU Index	612-129-00-5
EU classification	Flammable F Corrosive C
R-phrases	R11, R20/22, R34
S-phrases	(S1/2), S16, S26, S36/37/39
NFPA 704	75px 3 2 0
Flash point	−17 °C
Autoignition temperature	315 °C
Explosive limits	1.1–8.5%
LD50	770 mg kg−1 (oral, rat) >10 g kg−1 (dermal, rabbit)
Related compounds
Related amines	Diethylamine Triethylamine Diethylhydroxylamine Dimethylaminopropylamine Diethylenetriamine N,N-Diisopropylethylamine Triisopropylamine Tris(2-aminoethyl)amine Mechlorethamine HN1 (nitrogen mustard) HN3 (nitrogen mustard)
Related compounds	N-Methylethanolamine Dimethylethanolamine Diethylethanolamine Diethanolamine N,N-Diisopropylaminoethanol Methyl diethanolamine Triethanolamine Bis-tris methane Agmatine
14pxY (verify) (what is: 10pxY/10pxN?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Diisopropylamine is a secondary amine with the chemical formula (CH₃)₂HC-NH-CH(CH₃)₂. It is best known as its lithium salt, lithium diisopropylamide, known as "LDA". LDA is a strong, non-nucleophilic base.

Diisopropylamine can be dried by distillation over potassium hydroxide (KOH) or drying over sodium wire or sodium hydride (NaH) followed by distillation under N₂ into a dry receiver.

Diisopropylamine is also used for the synthesis of diisopropylethylamine (Hünig's base), by reaction with diethyl sulfate.